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These alterations not only extend its duration of action but also enable IGF-1 LR3 to circumvent binding with IGF-binding proteins, which typically impede the biological availability and efficacy of IGF-1

These cells also secrete anti-inflammatory cytokines (e.g., IL-10) that dampen M1 responses and facilitate tissue repair (137)

The effect was selective for visceral fat with little change in subcutaneous fat or BMI

doi: 10.1677/joe.0.1550079 135 PihokerCKearnsGLFrenchDBowersCY

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