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This paradox may be explained by the antioxidant paradox, where excessive scavenging of ROS disrupts their physiological role in capacitation and acrosome reaction (Dutta et al., 2022)

Lancet 397 , 23612371 (2021)

73 Direct metabolic profiling of follicular fluid has shown that the levels of pyruvate and lactate are significantly decreased during the development of PCOS

The application of recently developed research methods, such as genome-wide association analysis of human TB patients, may help to reveal the genetic etiology of TB and to identify key anti-Mtb intrinsic immune components