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Understanding and addressing our toxic burden is crucial for restoring health and preventing further harm

10.1016/j.cell.2015.10.072

10 The American Diabetes Association recommends gabapentinoids (e.g., gabapentin), serotonin-norepinephrine reuptake inhibitors (SNRIs) (e.g., duloxetine), and tricyclic antidepressants (TCAs) (e.g., nortriptyline) as first-line options

"A productivity collapse to end Earth's Great Oxidation"

Sarkar et al., 2020), which has been proposed as a conversion into an embryonic-like state recapitulating many events during embryogenesis, including the reactivation of embryonic signature genes, and cytoskeletal/ECM components, and lineage specification (Vortkamp et al., 1998