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Information sources Studies were identified by searching PubMed Medline, Ovid Medline, Embase, Scopus, Google Scholar, and the Cochrane Library to retrieve all available relevant articles

B12 deficiency can worsen tinnitus and lead to other symptoms like fatigue, muscle weakness, and nerve damage

Its unique structure and function make it a significant challenge to deliver drugs and therapeutic agents to the brain, requiring innovative strategies for the effective treatment of CNS disorders