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Diabetologia (2013) 56(9):198798

342 For example, tryptophan-derived metabolites produced by Lactobacillus can induce immunosuppression by influencing macrophage activity within the tumor, further supporting tumor growth and immune evasion

When activated, MC1R shuts down the inflammation signaling pathway called NF-kB and lowers pro-inflammatory cytokines like TNF-alpha and IL-6

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