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The study protocol was approved by the Ethics Committee of Minzu University of China and followed the guidelines of the Declaration of Helsinki

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Finally, many thankful regards go to Jorgete Constantin, Aparecida Pinto Munhos Hermoso and Renato Polimeni Constantin, from the University of Maring, Paran, Brazil, for their invaluable help during some experimental procedures

Therefore, understanding whether IF can mitigate these factors by improving both inflammatory and oxidative stress markers, as well as liver enzyme profiles, could offer a novel, non-pharmacological strategy for managing RA and its associated metabolic complications in this vulnerable population