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Description

Circulatory system Heart injury (e.g., caused by myocardial infarction, I/R, or anthracycline-based chemotherapy) is associated with an increased ferroptotic response with reduced GPX4 and increased iron accumulation

This persistent misconception causes much suffering to patients through the rejection it can lead to

Clinical Potential This review has introduced a few of the many disorders afflicting peripheral tissues or the CNS in which inflammation is implicated, but that is enough to recognize the therapeutic potential of influencing the kynurenine pathway by pharmacological interference