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Furthermore, we found that DRP1-driven mitochondrial fission is accompanied by disruptions in iron metabolism, creating a favorable intracellular environment for ferroptosis in ATC cells

F.RouenS.SiegfreidE.WrightD

2-[(2-Methyl-cyclopropylcarbonyl)amino]-N-(2-chloro-6-methylphenyl)-6-benzothiazolecarboxamide

Such stress-associated -cell states are known to display impaired incretin responsiveness due to reduced GLP1R signaling and diminished cAMP pathway activation (Luo et al., 2013)[Gao], suggesting that inflammatory axes linked to dysbiosis may differentially affect vulnerable -cell subpopulations