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(1991) documented that IV infusion of 2 g/m^2 raised plasma glutathione from 17.5 umol/L to 823 umol/L -- a roughly 47-fold increase -- with a half-life of approximately 14 minutes (Aebi et al., 1991)

Dyclonine and leucovorin promote OPC differentiation while maintaining the OPC pool in a mouse model of adult demyelination To further assess the pro-oligodendrogenic capacity of dyclonine (Sm5) and leucovorin (Sm11) in vivo in the context of myelin pathologies occurring later in life, we used the mouse model of adult focal de/remyelination induced by lysolecithin (LPC) injection into the corpus callosum (Fig

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Further confirmed that PNC-27 enters cancer cells and selectively disrupts mitochondrial membranes while leaving lysosomes intact, demonstrating dual cytotoxic mechanisms

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