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By inhibiting NNMT, 5-Amino-1MQ may support cellular NAD+ levels, which are critical for mitochondrial function, energy metabolism, and cellular health

Biochem Biophys Res Commun 379(1):133138 Keya SS, Mostofa MG, Rahman MM, Das AK, Rahman MA, Anik TR, Sultana S, Khan MAR, Islam MR, Watanabe Y (2022) Effects of glutathione on waterlogging-induced damage in sesame crop

These mechanisms likely work in synergy to drive ferroptosis in irradiated lens cells, with their relative weights varying depending on the specific radiation exposure conditions