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AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense

Importantly, the majority of studies in this area used the oversimplistic M1 and M2 macrophage classifications, whereas in recent years advancements have been made to study the more elaborate classifications of macrophages in the general immunology setting 90 , and this should thus be applied to the macrophages in wound healing setting 91

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Furthermore, the limited sample size in our animal study must be considered a potential constraint on the statistical validity and generalizability of the RNA-seq results

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