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Description

As an endogenous peptide responsive to exercise and nutrient cues, it regulates pathways involved in energy homeostasis and cellular adaptation

MC: Writing original draft, Writing review and editing

2017;7(3 Suppl):95S-115S

Amino acid dysregulation metabotypes: potential biomarkers for diagnosis and individualized treatment for subtypes of autism spectrum disorder

It is possible that these variants have impaired folding and localisation, although R169W has previously been shown to localise normally to the membrane 53