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instead, their performance gradually degrades over time and usage

(2002) Alcohol activates activator protein-1 and mitogen-activated protein kinases in rat pancreatic stellate cells J

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They can target JAKs, STATs, and/or receptors and may also involve other proteins of the proteasomal degradation pathway (123)

These results suggest that cancer cell metabolism significantly differs from healthy cells and likely requires more energy for growth and division