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Disturbances in the intestinal flora can lead to an over-activation of the host immune system, which induces an inflammatory state, and both intestinal inflammation and IBD are associated with intestinal flora dysbiosis (Shen et al., 2018)

Thermal shift assay (TSA) Samples were prepared by using a final concentration of 0.25 mg/ml TGR diluted in TGR reaction buffer to the desired volume

Nutrients 13:1602

Through excessive ROS production, DOX has been shown to promote apoptotic signaling

These observations suggest that GPX4 expression and ferrous iron levels are upregulated in anti-colorectal cancer drug-tolerant cells and could hence be therapeutic targets for the selective eradication of persister cells