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Zugleich traten bei 32% der Untersuchten Nebenwirkungen auf, darunter Leberfunktionsstrungen und ein Fall von Anaphylaxie (Alzahrani et al., Cureus 2025, PMID 40013212)

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When evaluating the HSC compartment in middle-aged and aged WT animals, we observed an increased frequency of EPCR SLAM, LSK SLAM, and LT-HSCs, indicative of HSC expansion, an established hallmark of aging, that was more prominent in aged compared to the young or middle-aged animals