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Strategies Against Microbial Biofilms Since biofilm-related infections and the challenges in their treatment have been regarded as major threats to human health, strategies to address this problem have been developed in recent years (Figure 3)

Down-regulation of TMAO levels by dimethyl-1-butanol (DMB), a TMA formation inhibitor, is able to ameliorate the cognitive deterioration and long-term potentiation (LTP) in APP/PS1 mice and decrease amyloid- (A)1-42, -secretase, and -secretase-cleaved C-terminal fragment (CTF) levels in the hippocampus (Gao et al., 2019)

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Iran J Basic Med Sci

CHO cells were maintained at 37C in 5% CO 2 in the F12 (HAM) medium supplemented with 10% foetal bovine serum, 1% penicillin/streptomycin solution, hygromycin 100 g/mL, and puromycin 1 g/mL for stable selection