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A 2024 phase 2 trial published in Nature Medicine enrolled 98 adults with confirmed obesity and fatty liver, treating them with retatrutide once weekly for 48 weeks

Ardura-Fabregat A, Boddeke EW, Boza-Serrano A, Brioschi S, Castro-Gomez S, et al

Originally discovered in human plasma, this copper-bound peptide plays a key role in tissue remodeling, collagen synthesis, and the reactivation of dormant hair follicles