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Zecca, The role of iron in brain ageing and neurodegenerative disorders

10.3389/fnut.2024.1419811 32 BonnetM

Breg cells are capable of inhibiting the trophic signals of Th1 and Th17 responses which are indispensable in the pathogenesis of autoimmunity (115)

93 Unlike other GPX4 inhibitors, ML210 is a prodrug that within cells is converted to the active form -nitroketoxime JKE1674 that covalently inhibits GPX4