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Studies in the MRL/lpr lupus-prone mouse model have demonstrated that gut dysbiosis can induce intestinal oxidative stress, compromise the gut barrier (evidenced by reduced ZO-2 and elevated fecal albumin and IgA), promote bacterial translocation, and exacerbate systemic inflammation and autoimmune responses [37]

Methylcobalamin is felt to be superior to cyanocobalamin because it does not require methylation for activation in the body

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Al-Sadi R, Guo S, Ye D, Ma TY (2013) TNF- Modulation of Intestinal Epithelial Tight Junction Barrier Is Regulated by ERK1/2 Activation of Elk-1

Dtoxifiant : en se liant aux substances dltres, il les rend hydrosolubles et permet leurs limination par les urines et la bile