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Zheng, F

It's becoming increasingly challenging to ignore the sheer breadth of its potential

Literature indicates that -tocopheryl succinate (-TOS), a redox-silent analog of vitamin E, can inhibit the interaction of Baks BH3 domain with Bcl-2 and Bcl-xL, weakening their biological activity and increasing mitochondrial outer membrane permeability, leading to apoptosis in breast and colon cancer cells (202)