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J Clin Invest 131(23):112

doi: 10.1042/bst20130220 84 WoloskerH.ShethK

MayoClinic 2012)

Collectively, these results demonstrated that EVs released by TfR-deficient macrophages could not alleviate cardiac iron overload, relieve ferroptosis and restore cardiac function, highlighting the indispensable role of TfR on macrophage-derived EVs in their protective effect against MI-induced myocardial injury

Results Absence of promoter proximal NRF2 at NRF2 signature genes To identify critical pathways downstream of NRF2 activation in cancer, we sought to define a core set of genes and other features associated with NRF2-dependent growth across an expansive panel of cancer cell lines