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[DOI] [PubMed] [Google Scholar] 124.Keith B., Johnson R.S., Simon M.C

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Glutathione prevents high glucose-induced pancreatic fibrosis by suppressing pancreatic stellate cell activation via the ROS/TGF/SMAD pathway

This review examines the molecular mechanisms underlying ASM-associated oxidative stress in clinical, non-kindled/kindled preclinical, as well as non-epilepsy models, and highlights evidence demonstrating the ability of ascorbic acid to attenuate ROS accumulation, enhance endogenous antioxidant defenses, and modulate redox-sensitive signaling pathways implicated in epileptogenesis and ASM-induced toxicity

10.1007/s13346-014-0199-6 69 GuglielmoA.SabraA.ElberyM.CerveiraM