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Description

Outliers were identified using the ROUT (robust regression and outlier removal) method with a Q value of 1%

This condition may be associated with immunosuppression, in view of the lower availability of this amino acid for the immune cell metabolism [1]

Como anlogo de la clase molecular de factores de crecimiento similares a la insulina , una variante modificada de IGF1 activa el receptor IGF1R (tirosinaquinasa) y las vas de sealizacin aguas abajo PI3KAKTmTOR y RASRAFMEKERK, lo que lo convierte en una herramienta relevante para modelar respuestas anablicas y proliferativas in vitro e in vivo (Wikipedia: IGF1

Data availability The RNA-seq data generated in this study have been deposited at Gene Expression Omnibus (GEO) database under accession code GSE280421