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Small changes in the time of administration relative to ischemia can shift PRPs effect from anti-apoptotic to apparently pro-inflammatory, as shown in models where PRP given before ischemia produced stronger protective outcomes than when applied at reperfusion 52

When you fix your hormones, you fix your life. Thats the headline from a new episode of the Balls Deep podcast

Muir, A., Danai, L

Indeed, T FH cells are increased in SSc peripheral blood and in the skin, they present an activated phenotype, increased capacity to produce IL-21, and higher capacity to stimulate the differentiation of CD19+CD27+CD38hi B cells and their secretion of IgG and IgM through the IL-21 pathway than healthy controls

This exploitation by cancer could serve as a potential therapeutic strategy for targeting the disease