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They showed that as the concentration of LPS increased, the activity of Caspase3/7 rose, the expression of the pro-oncogene Bax increased and the tumor suppressor gene Bcl-2 decreased (Liu et al., 2020) ( Figure 1 )

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Additionally, baicalin and berberine have also been shown to lower TMAO levels (Liu et al., 2020)

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This highlights the urgent need for innovative adjunctive chemotherapy strategies to enhance current treatments, mitigate side effects, and reduce toxicity without compromising efficacy (380)