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Description

10.1542/peds.113.5.e465 68

N -Acetyl- S -(1,1-difluoro-2-fluoromethoxy-2-[trifluoromethyl]ethyl)-L-cysteine sulfoxide was identified and quantified in the urine of rats given fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (Sheffels et al

[Epub Online ahead of print] 10.1515/revneuro-2021-0118 Rev

However, proton leak through the membrane due to damage of the mitochondrial membrane and ETC, further increase oxygen consumption (uncoupled respiration) and exaggerate ROS production