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The Pathogenesis of Epilepsy One of the main causes of epileptic seizures is believed to be the abnormal activity of cortical neurons, and the abnormal discharge of these neurons has mostly been related to the loss of specific subarea inhibitory and excitatory neurons, neurotransmitter transmission and imbalance, synaptic recombination, axonal germination, as well as the change in the glial cell functioning and structure

Future research should prioritize large-scale, multicenter trials that assess not only the clinical outcomes but also the underlying mechanisms of action of antioxidants in the context of DN

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Gut microbiota also plays a critical role in maintaining host health, particularly by regulating metabolism (44)