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Digestive Discomfort The most frequently reported side effects are gastrointestinal

The disrupted synaptic function in ASD relates to higher-level phenotypic changes as observed in other neurologic disorders and may result in altered sensory processing, cognitive deficits, hyperactivity, and seizures by affecting the balance between excitatory and inhibitory neurotransmission [4]

Nonetheless, clinical trials involving both healthy individuals and those with mild cognitive impairment or AD are warranted to investigate whether melatonin can enhance the glymphatic systems efficacy in reducing brain concentrations of A and tau

High levels of miR-124 in serum inhibit the expression of Fpn, leading to iron accumulation and ferroptosis in cells ( FIGURE 1 TABLE 1 The regulatory mechanism of ferroptosis

Quantifications of the Western blots used to create Fig