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Regular physical activity, particularly endurance and aerobic workouts, is another excellent way to lower TMAO levels

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The exact cause isnt always clear, but common contributors include: Trauma or injury to the penis (often unnoticed) Surgery, especially for prostate cancer Genetics, including a family history of Dupuytren's contracture Inflammation, ageing, or smoking (Restorative Health Clinic, 2025) Over time, scar tissue forms inside the penis (within the tunica albuginea), causing it to bend or curve during an erection