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That's a specific and meaningful distinction, even accounting for the fact that the evidence comes from cell studies rather than large clinical trials

Vilanterol.Exceptions: Inhaled salbutamol: maximum 1600 micrograms over 24 hours in divided doses not to exceed 600 micrograms over 8 hours starting from any dose

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This balance between size and specificity is frequently cited as a design achievement of the original Monash research program and is one reason the molecule has endured as a reference compound across multiple laboratories