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Staff et al., 2013

Hu Z, Li Y, Sommerfeld M, Chen F, Hu Q

MOTS-c activates AMPK pathways that improve GLUT4 glucose transport, restoring cellular glucose uptake without the GI side effects of metformin.5 For adults managing prediabetes or metabolic syndrome, this is clinically significant

It is a relatively common phenotype of asthma, affecting primarily adults but also children with physician-diagnosed asthma and, in some cases, subjects with no previous history of asthma