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Mechanism of Action: Lidocaine is an amide-type local anesthetic that works by inhibiting sodium ion influx into nerve cells

Dose Selection: The trials evaluated doses ranging from 0.25 mg to 54 mg, with higher doses showing increased gastrointestinal effects

As an alternative solution to address the abovementioned issues, the introduction of cell-homing agents into scaffolds to recruit MSCs from subchondral bone for cartilage regeneration is an attractive option that could avoid the usage of autologous cartilage tissue and reduce immune rejection 17,19,20

Clinical efficacy and body composition changes with sodium glucose cotransporter 2 inhibitor/glucagon-like peptide-1 agonist combination therapy in patients with type 2 diabetes mellitus-associated nonalcoholic fatty liver disease

For skin brightening: results may appear within 812 weeks with consistent daily use