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A role for prolyl hydroxylase domain proteins in hippocampal synaptic plasticity

Prior to the onset of symptomatic diabetes, specific antibodies, including islet cell autoantibodies (ICA), can be detected in the blood of high-risk individuals (68)

This quantity supports multiple experimental procedures, including receptor binding studies, cellbased assays, and animal model research

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While targeting glutamine pathwaysparticularly GLS1 and -KG metabolismpresents promising antifibrotic potential, the cell type-specific and compensatory mechanisms highlight the need for precise therapeutic strategies to effectively harness glutamine-targeted interventions in IPF (Fig