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10.1016/j.neurobiolaging.2017.09.024 Neurobiol

There is an irresistible urge to scratch the tongue on the teeth to stop the itching

Glucocorticoids can suppress glycolysis by blocking the transcriptional and post-translational effects of hypoxia-inducible factor 1 (HIF-1) in macrophages, while promoting glutamine metabolism to enhance TCA cycle flux and succinate metabolism, thereby preventing intracellular succinate accumulation and facilitating the conversion of macrophages from the M1 to the M2 phenotype (112, 113)