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[DOI] [PMC free article] [PubMed] [Google Scholar] [201].Usui-Ouchi A, Friedlander M, Anti-VEGF therapy: higher potency and long-lasting antagonism are not necessarily better, J

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For example, a 2021 review discussed possible ways NAC could help counter ROS-related survival, metastasis, and drug-resistance pathways in triple-negative breast cancer.39 And in a small uncontrolled pilot study involving women with breast cancer, NAC supplementation was associated with reduced markers of tumor cell proliferation.40 But animal research has found concerning effects in other contexts

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About the study The phase 3a, multicenter, randomized, double-blind, placebo- and active-controlled REDEFINE 1 trial enrolled 3,417 adults across 22 countries