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There is also preliminary evidence that benfotiamine, a derivative of thiamine (B-1), may lessen nerve pain in people with diabetes, but more research is needed to confirm a benefit

One study found that people with migraine with aura (one that causes sensory disturbances like vision changes, blind spots, or flashes of light) who took B vitamin supplements with B6, B9, and B12 had reductions in migraine-related disability from 60% to 30%

I guess, it's always a difficult balance between testing for things that are likely and things that are less likely, and also the costs of these tests are not necessarily insignificant for many of us as well

Characterization of the targeting signal in mitochondrial -barrel proteins