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Vitamin B6 (pyridoxine) serves as a necessary cofactor in the folate cycle, playing a role in neurotransmitter synthesis, such as dopamine, serotonin, GABA, noradrenaline, and melatonin

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As a result, you may experience the following symptoms ( tiredness a lack of energy shortness of breath difficulty concentrating more frequent bouts of illness difficulty regulating your body temperature or often feeling cold pale skin heart palpitations headaches hearing ringing, hissing, or buzzing noises inside your head itchiness a sore tongue or difficulty swallowing changes in the way food tastes hair loss cravings for non-food items, such as ice or dirt also known as pica painful open sores in the corners of the mouth spoon-shaped nails an uncontrollable urge to move your legs also known as restless leg syndrome If youre experiencing any of these symptoms, consider discussing diagnostic testing options with your healthcare provider to identify or rule out low iron levels or IDA

Histological analysis For light microscopic investigation, liver and kidney tissue samples were fixed in 10 % neutral buffered formaldehyde