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For example, a library of recombinant cytokine-encoding nucleic acids can be screened by testing the ability of cytokines encoded by the nucleic acids to activate cells which contain a receptor for the cytokine

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STAT3 STAT3 activation in GBM is driven by multiple receptor tyrosine kinase pathways, including the EGFR, PDGFR, and c-MET pathways, along with the loss of negative regulators such as protein tyrosine phosphatases, suppressors of cytokine signaling, and protein inhibitors of activated STAT3

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acidifaciens more than glucose (Extended Data Fig

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