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The toxicity models described earlier are also based on acute toxicity and a narcotic mode of action, although (as this chapter highlights) there are many other mechanisms of action and sublethal effects that have implications at the individual, population, and ecosystem levels as a result of both acute (not lethal and also including delayed responses) and chronic longer-term exposures

Thiamine is crucial for energy metabolism, and its deficiency can cause severe neurological and cardiac disorders

It also an important part of the collagen formation

Chronic volume depletion of body fluids from diuretics (medicine that promotes urination) and poor fluid intake both lead to dehydration and may act similarly to predispose to cramps, especially in older people

Free radicals are highly reactive compounds created in the body during normal metabolic functions