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J Physiol Investig 68(2):9199 Panagaki T, Janickova L, Petrovic D et al (2024) Neurobehavioral dysfunction in a mouse model of down syndrome: upregulation of cystathionine -synthase, H(2)S overproduction, altered protein persulfidation, synaptic dysfunction, endoplasmic reticulum stress, and autophagy

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2018;13:e0196321

Furthermore, elevated levels of markers for glial cells (GFAP and Sox-10) and multiple pro-inflammatory cytokines are found in colon biopsy samples from individuals suffering from PD (65)

The primary risk is bacterial infection a vial left at room temperature for 12+ hours can harbor pathogens that cause injection-site abscesses, cellulitis, or systemic infection if they enter the bloodstream