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Active oxygen is the most oxidizing substance in our body, so it oxidizes the cells causing cellular aging

Stephanopoulos, N., Tong, G

For instance, GSH deficiency has been detected in mice brain slices [48] and in cultured hepatocytes [49] following treatment with inhibitors of the CSE enzyme

For example, in either LPS or chronic social defeat stress (CSDS) models of depression, sulforaphane prevented stress-induced increases in pro-inflammatory cytokine production and restored anti-inflammatory cytokine production (Tang et al., 2022)

These authors reported that such epigenetic factors could explain 11.6% of the variance in serum UA, substantially greater than the 7.7% explained by genetic variability alone