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Methylcobalamin is available as an unlicensed supplement but is not a routinely recommended medicinal product in the UK and should not be substituted for licensed preparations without clinical advice

In summary, phase-separated condensates exhibit a functional duality: they maintain cellular homeostasis under physiological conditions yet can drive pathological dysregulation when perturbedthereby acting as pivotal determinants of cell fate

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The amino acid serine, a down-line metabolite generated from betaine via the homocysteine remethylation pathway, is also necessary