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The effect is most noticeable as more even skin tone rather than dramatic lightening, and it works best in patients with hyperpigmentation, melasma, or uneven pigmentation rather than as a generalized skin-lightening agent

Causes and consequences of impaired methionine synthase activity in acquired and inherited disorders of vitamin B12

Our results are in line with those of Schurr et al

Since GHK-Cu levels decline naturally with age, ongoing supplementation helps maintain the gains achieved during intensive treatment phases