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It also upregulates the expression of the gastrointestinal barrier proteins ZO-1 and occludin in MPTP-treated mice, improves intestinal barrier function and gastrointestinal dysfunction, and consequently exerts a neuroprotective effect indirectly via the gut-brain axis ( Another study demonstrated that administration of neohesperidin, the primary active component of citrus fruits (25 and 50 mg/kg, administered for 24 days), significantly alleviated MPTP-induced damage to dopaminergic neurons in the substantia nigra-striatal pathway of PD mice, increased levels of striatal dopamine (DA) and its metabolite DOPAC, and improved motor dysfunction

Drug and Statistics (DAS) software (Version 3.0, Shanghai University of Traditional Chinese Medicine

The Importance of Vitamin C for Skin Vitamin C, also known as ascorbic acid, is integral for collagen synthesis, giving our skin structure and firmness

Despite their extensive application, challenges remain in optimizing bioavailability, understanding absorption mechanisms, and exploring synergistic interactions with other food components