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Regarding the mitochondrial dysfunction featuring the disease, morin and mangiferin displayed the ability to attenuate membrane potential loss in neurons (308), as well as quercetin which also enhanced mitophagy by upregulating Pink and Parkin gene expression (309)

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Rawson Creatine Supplementation and Brain Health PMID: 33578876 PMCID: PMC7916590 DOI: 10.3390/nu13020586 J R Poortmans, M Francaux Adverse effects of creatine supplementation: fact or fiction

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