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doi: 10.3892/ol.2019.9933 111 LiuTChenXGuanGZouCShenSWuJet al

doi:10.1053/j.gastro.2017.01.031 4

Mechanism of Action (Research Context) Pre-clinical research in lab models shows that BPC-157 modulates angiogenic growth factors and nitric oxide pathways, whereas TB-500 has an effect on the regulation of actin binding protein and cellular migration

In our study, neither translocation or phosphorylation of p65, nor protein expression of NLRP3 and IB- were altered by HNE treatment (0.3-3 M) after LPS stimulation (Fig