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At 5 mg/mL, even moderate doses result in very small volumes (300 mcg = 0.06 mL, ~6 units)

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However, these antigens have the drawbacks of unstandardized preparation methods and are therefore not reproducible across laboratories [35]

Of interest, a post-hoc analysis of the EVOLVE trial in patients on hemodialysis recently showed that cinacalcet administration, which allows improved PTH control, resulted in a significant decrease in the incidence of calcific uremic arteriolopathy as compared to placebo (239)