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Molecular mechanism and biological functions of c-Jun N-terminal kinase signaling via the c-Jun transcription factor

Luquero A, Badimon L, Borrell-Pages M

Fibroblasts from patients with HGPS show increased levels of basal phosphorylated histone variant H2AX (H2AX) and increased amounts of phosphorylated checkpoint kinase 1 (CHK1) and CHK2, compared with unaffected fibroblasts (Liu Y

7-Keto-cholesterol and cholestan-3beta, 5alpha, 6beta-triol induce eryptosis through distinct pathways leading to NADPH oxidase and nitric oxide synthase activation