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Due to deficiencies in mtDNA repair mechanisms, lack of histone protection, and the proximity of mtDNA to the IMM where ROS are generated, mtDNA is highly susceptible to oxidative damage [81]

It can be concluded that our goal-orientated manipulation through homology modeling, molecular docking, and site-directed mutagenesis is effective for improvement of DCM dehalogenase activity and investigation of correlation between structure and function

Ansboro, S., Roelofs, A

(35837678) For patients who refuse buprenorphine therapy , inpatient methadone may be utilized even if there isnt a pre-defined discharge strategy

10.1007/s00296-016-3551-y 287