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The medium was replaced every 2 days until 90% confluency was reached

Crohns Colitis 16 , 506510 (2022)

They exhibited fewer side effects or improved pharmacokinetic profiles, establishing them as first-line drugs for AD

In parallel, IRF3, activates the Receptor-Interacting Protein Kinase 1 (RIPK1)-IFN activator (RIPA) pathway to induce mitochondrial apoptosis, though temporally suppressed by X-Linked Inhibitor of Apoptosis Protein (XIAP) to prevent premature cell death (62)